Karolinska Institutet31 июл., 15:46Link to publication ⬇️ link.springer.com/article/10.1...Single-cell analysis of the progeria arterial wall reveals progerin-induced progressive, cell type-specific dysfunction and somatic mutation accumulation - Genome MedicineBackground The premature aging disorder Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by de novo LMNA mutations producing the aberrant Lamin A isoform progerin. HGPS patients die from cardiova...link.springer.com