Commensal gut bacteria are capable of rapid adaptation fueled by enormous mutational input. Independent de novo adaptations can therefore arise quickly in individual hosts. @contaminatedsci.bsky.social and group have been influential in driving this line of thinking. www.cell.com/cell-h... 2/n

Adaptive Evolution within Gut Microbiomes of Healthy PeopleBacteria acquire adaptive mutations during infections, but the role of mutations in the gut microbiome is unknown. Zhao and Lieberman et al. report that Bacteroides fragilis adapts via mutation within...www.cell.com