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Публикация

Today I'm posting a blog about another ridiculous antibody blunder. Dozens of papers in the senescence and ageing field have mistakenly used an antibody for E. coli β-galactosidase when trying to stain for the human protein with the same name. forbetterscience.com/2026/07/21/d...

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Ответы

Surely they would have caught this when they validated the antibody?

Ответ для Morten Grøftehauge

Must be sarcasm 😋

They're really trying to make bacteria live forever...now their secret is out.

It’s a rubbish-ridden field - probably just part of the reason.

Ответ для Laurence Pearl 🔥

Yes, we're all going to live forever and age backwards, the people on the bleeding edge just need to work out how to read antibody names first.

how do you mix those up? accidentally ordered the wrong ones? mislabelling? especially multiple labs..

Ответ для A_lethe_ion

Professor says to student: Order an antibody for beta galactosidase and choose the cheapest one. Student googles "beta galactosidase antibody, cheapest one". That's it I think 🤷‍♀️ A forgivable error but should have been caught by controls and review. Some vendors didn't help.

Ответ для A_lethe_ion

If you’re looking for a new antibody that you’ve never used, you usually go to previously published papers to use as guidance and to compare like for like. In this case is likely that someone from a “big lab” made the initial mistake and then it got replicated 😬