Chemists have a new tool that could make it safer to synthesize fluorinated pharmaceuticals, agrochemicals, and materials. The transformation is a riff on the Appel reaction, which turns alcohols into alkyl halides but until now had been incapable of making alkyl fluorides. #chemsky 🧪
Appel reaction can finally fluorinateThe classic alkyl halide–making reaction can, at long last, be used to generate alkyl fluoridescen.acs.org