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It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪

www.biorxiv.org
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20 прямых ответов · 54 сообщений

Ответ для Estibaliz Gómez de Mariscal, PhD

Thanks! :D

Wow! Congratulations! May I invite you to celebrate with a delicious slice of Prince Far ITEC? #PaperThemeTune pressuresounds.bandcamp.com/track/the-ri...

The Right Way, by Prince Far ifrom the album Crytuff Dub Encounter Chapter Onepressuresounds.bandcamp.com
Ответ для Sally Lowell

Haha yesssssss thanks, Sally!

In case you are looking for a journal, consider journals.biologists.com/jcs/pages/im... @jcellsci.bsky.social

CFP | Imaging | Journal of Cell Science | The Company of BiologistsCFP | Imaging | Journal of Cell Science | The Company of Biologists Special Issue: Imaging Cell Architecture and Dynamics Journal of Cell Science (JCS) invites you to submit your latest...journals.biologists.com

Congratulations 🎉 🎉 it looks awesome! Looking forward to reading it in more details

Ответ для Guillaume Jacquemet

I keep telling Guoqiang that you're the target audience hahah thanks man!

Oh wow, that looks very powerful AND user friendly - congrats!!

Ответ для Joachim Goedhart

Thanks a lot, Joachim!

I am also going to activate the @florianjug.bsky.social signal here

Ответ для MadScientist

👀 absolute must read… must try… Looks great… congrats! 🎉

Ответ для Florian Jug

Thanks! It's been very fun tbh

We found that ITEC (which can follow cells reliably across hundreds of time points (!!!) ) can reconstruct the cell lineages of somites from mixed domains at the onset of gastrulation, and also that cells in the margin (which involute and are hard to track) change their gene expression 🧪+

Ответ для MadScientist

This was a collab between us (Yinan in Basel) and the lab of Guoqiang Yu (now in Tsinghua U) that started a long ago. Lots of meetings and lots of tinkering, but super happy with the results. All the code is open and user friendly, so let us know what you think! 🧪🐟

Ответ для MadScientist

(also thank you @paveltomancak.bsky.social for Fiji/BDV and @jytinevez.bsky.social for Mastodon because let me tell you we've spent a lot of time in there)

Ответ для MadScientist

I hope you are reviewing the Mastodon paper 😉

Ответ для paveltomancak

God I wish

Ответ для MadScientist

"Why doesn't it make a PLOP sound when you merge two tracks?"

Ответ для MadScientist

Feature request @jytinevez.bsky.social

Ответ для MadScientist

We have to hope for other fans then 🤷‍♂️

Ответ для paveltomancak

I mean, reviewing that paper at this point is like seeing an old friend. That's an automatic 'accept as is'. It's more like catching up than reviewing.

Ответ для MadScientist

Resisting the desire to tag the journal in question. Not @natmethods.nature.com 😆

Ответ для paveltomancak

Do it man. Let me send them a letter. I'd be happy to!

Excellent - many congratulations to all involved. Though did no one push to put an ‘H’ at the start of the algorithm descriptor such ‘Highly’, so the acronym could be ‘HITEC’?

Congrats!!! Killing it!

Ответ для Ethan (Chee Kiang) Ewe

Thanks my man!

so cool !!!! congratulations! 🤩 eager to try this out @mads100tist.bsky.social

Ответ для Diana Pinheiro

Yessssss hahahah thanks!

This is awesome. I will never forget seeing @blockintheback.bsky.social presenting her first code that did 3D tracking, like... a bunch of years ago and having my mind blown.

Ответ для BWJones

It's better than magic: it's science

Ответ для MadScientist

As Arthur C Clarke would say: "Any sufficiently advanced technology is indistinguishable from magic"

Ответ для MadScientist

Can I make a t-shirt print of this sentence?

Ответ для Dr Zeinab Rekad 🔬🧬🧪

Only if you take a pic afterwards!

Ответ для MadScientist

Hahah better: I can send you a vectorial copy of the design so you can print it too 😊

Congrats! Looks amazing!

Ответ для Damian Dalle Nogare

Thanks! :)

Congratulations!!! 👏🏻👏🏻🥳

Ответ для Elena Camacho Aguilar

Thanks!

Ответ для Maureen Barr

Yesssss

Did I do this right? (congrats! 😜)

elmo from sesame street is standing in front of a fire with the words `` death to all who wronged me !!! ''ALT: elmo from sesame street is standing in front of a fire with the words `` death to all who wronged me !!! ''media.tenor.com
Ответ для Maxim Greenberg

Bahahhaha yesssss

Ok!!! Will give at shot, we’re tracking survival in organoids now - I’ll nag!

Congratulaciones 🥳 que pasada! Directo a la reading list 🔥🔥🔥🔥

Ответ для Sergi Roig Puiggros

Gracias! :D

Congrats! This seems quote powerful... I wonder how much it could be adapted for the study of organogenesis or tissue environment organization in humans.

Ответ для Damian Maseda

In theory, it should be applicable off the bat. We've tried it with cells in vitro and it works hahah

Awesome 🤩 congratulations!!!

Ответ для Dan 🐟 C

Thanks, my man!