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Octameric dGTPase assemblies mediate broad anti-phage defense | Nature Communications
Octameric dGTPase assemblies mediate broad anti-phage defense - Nature CommunicationsDeoxyguanosine triphosphatases (dGTPases) are nucleotide-depleting enzymes that contribute to antiviral defense. Here, the authors reveal widespread and structurally diverse dGTPases and characterize oligomeric dGTPases in distinct assembly states, providing insights into their architecture, activation, and regulation.www.nature.com