New in @embojournal.org from @birgitkemmerling.bsky.social's lab: HIR2 assembles into giant ring-like complexes at the plasma membrane, shaping receptor dynamics and immune signalling. Genetics + biochem + super-res imaging + AF3 modelling, all in one! Check it out👇 link.springer.com/article/10.1...

The Arabidopsis SPFH protein HIR2 modulates receptor signaling and plasma membrane organization - The EMBO JournalPlant plasma membrane proteins are organized into distinct domains; however, the principles that govern this spatial organization are not fully understood. HYPERSENSITIVE-INDUCED REACTION (HIR) protei...link.springer.com